Description
Multimodal Gel for PIH, Melasma, and Acne-Related Pigmentation
Formulated for professional protocols.
Product Overview
Tiracn Gel is a clinically oriented formulation developed to manage post-inflammatory hyperpigmentation (PIH), melasma, and residual acne discoloration through a synergistic combination of skin-renewing, pigment-suppressing, and antioxidant agents. The product is built around Tretinoin 0.05%, paired with Tranexamic Acid and Kojic Acid, known for their complementary roles in melanin inhibition.
Its lightweight gel texture makes it suitable for acne-prone, oily, or sensitive skin within evening treatment regimens.
Indications
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Post-inflammatory hyperpigmentation (PIH)
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Mild to moderate melasma
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Acne-related dark spots and uneven skin tone
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Photoaged skin requiring gentle resurfacing
Mechanisms of Action
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Tretinoin 0.05%: Stimulates keratinocyte turnover and enhances dermal collagen synthesis. Facilitates penetration of other actives and reduces follicular hyperkeratinization.
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Tranexamic Acid: Interrupts the plasminogen activation pathway, downregulating melanocyte activity in UV-induced and inflammatory pigmentation.
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Kojic Acid: Inhibits tyrosinase activity; acts synergistically with TA for melanogenesis suppression.
Clinical Usage Guidelines
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Recommended Application: Apply in the evening to affected areas or full face after gentle cleansing. Use 2–3x/week initially, increasing frequency based on tolerance.
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Duration: Ideal for 6–12 week protocols or until desired pigment reduction is achieved.
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Maintenance: May transition to non-retinoid brightening product once pigmentation improves.
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Sun Protection: Mandatory use of broad-spectrum SPF 50+ during treatment and for at least 4–6 weeks post-treatment.
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Combination Protocols: May be integrated into regimens with oral TA, laser toning, or microneedling, spaced appropriately.
Contraindications
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Pregnancy and lactation
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Active dermatitis, eczema, barrier-compromised skin
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Recent chemical peels, ablative procedures (wait until full re-epithelialization)
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Known hypersensitivity to any ingredient
Ingredients
Active Ingredients: Tretinoin 0.05%, Tranexamic Acid, Kojic Acid, Vitamin E, Aloe Barbadensis Leaf Juice
Other Ingredients: Alcohol, Ammonium Polyacryloyldimethyl Taurate, BHT, Phenoxyethanol, PEG-40 Hydrogenated Castor Oil, Ethylhexylglycerin, Water
Precautions
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For external use only
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Mild irritation may occur during initial use (e.g. peeling, dryness)
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Do not use on broken, inflamed, or recently treated skin
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Not suitable during pregnancy or breastfeeding
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Avoid combining with other strong actives unless advised by a professional
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